Post-Oophorectomy Estrogen Therapy May Not Increase Breast Cancer Risk in BRCA1 Carriers

Hormone replacement therapy (HRT) may not increase the risk of breast cancer among BRCA1-positive women who undergo preventative oophorectomy, according to a study published in JAMA Oncology.¹

For this prospective study, researchers evaluated the outcomes of 872 BRCA1carriers without any personal history of cancer who underwent preventative bilateral oophorectomy. Participants completed a questionnaire detailing HRT use at baseline and every 2 years thereafter.

Read more from Cancer Therapy Advisors by James Nam, PharmD, about Post-Oophorectomy Estrogen Therapy May Not Increase Breast Cancer Risk in BRCA1 Carriers.