Researchers identify underlying genetics of deadly gynecological tumors

Researchers have unveiled the genetic landscape of carcinosarcomas (CSs), some of the most deadly tumors in ovarian and uterine cancers, and they say their findings may aid in the development of new treatments.

Although CSs comprise only 2 to 5 percent of all uterine malignancies and 1 to 2 percent of all ovarian tumors, they are highly resistant to treatments like radiation and chemotherapy, according to Yale University researchers, who conducted the study. Overall, endometrial and ovarian cancers claim about 14,270 lives annually in the United States. More than 76,160 new cases are diagnosed each year.

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